| SAD | A 3D Graphical Interface for a Petroleum Systems Model |
| SAMSAT | Satellite Arsenal Management Simulation and Analysis Tool |
| Sasquatch | An Interactive System for BugBuster Scheduling |
| SatisTraktion | Spacecraft Status Visualization |
| SCAT | Graphical Interface for Fluid Dynamics |
| SchedMan | Comprehensive Web-Based Scheduling System for ITLL |
| Schwinners | A Corporate Intranet for Schwinn/GT |
| Scuzzy | SCSI Interface Test Package |
| Sega | Workgroup Management Suite |
| Segovia | A Visual Development Environment for Menuet/CX |
| Shale | Virtual and Physical Object Interaction |
| Shaman | The Children's Museum of Denver Weather Project |
| SHMOO | A Call-Processing Feature Management Tool |
| SHOGuN | Online Sales Tool for Order Creation |
| Show and Tell | A Class Library for the Construction of Electronic Brochures |
| SINBAD | Signature Based Anomaly Detection |
| SINN | Remote Power Management for PC Networks |
| SketchCraft | A Sketch-Based, Physics-Enabled Video Game |
| SKID | Skills Inventory Data Base |
| skynet | Software for an Unmanned Aerial Vehicle |
| SLICE | 2D Graphics Widgets for Visualization Application |
| SLY | The Children's Museum of Denver Personal Science Lab |
| S.M.A.G. | Sparkle Magic API for Graphics |
| SMILE | An Interactive Multi-media Tutorial Engine |
| smrt | 3D Media Center |
| SnakeBound | Internet Domain Name Services Manager |
| SNaPS | .NET 3D Animator for Micro Saint Sharp |
| Snow Crash | A Dynamic VRML Data Visualization Tool |
| SOAP On A ROPE | A SOAP/Linux LONWORKS Network Services Server |
| SoftCORE | HVAC Control System for a Solar House |
| SORI | StarOffice-Based Requirements Management |
| S.O.S. | User Service Request and Tracking System |
| Space Balls | Commanding, Monitoring, and System Log Parser for Payloads on the International Space Station |
| SPAM | Network-Based Appointment and Messaging System |
| SpeakEasy | A Voice-Based Event Notification Server |
| SPECTRE | A Classroom-Friendly Technique for Viewing Solid Objects |
| SPEED | Security and Privacy Enhanced Encrypted Document Management System |
| Spelunk | IP Packet Content Filtering and Pattern Discovery in Linux |
| SPIDER | Low-Cost Robotic Control System |
| Spiral | Turntable Control and Instrumentation Interface |
| splat | TCP/IP Based JavaScript Debugger |
| SPORK | Visual Printer Network Management |
| Squash | Access and Conversion of Large Data Sets |
| STARRSS | A Comprehensive Environmental Model for the Utility Industry |
| StrangeBREW | BREW-Based Cell Phone Simulation Game |
| STRAPPS | A Tool for Construction of Functional Models of Distributed Applications and Protocols |
| Stylus3 | 3D Paint Application for a 3D Graphics Animation System |
| SUNBURN | An Interactive User Interface for a Solar Building Educational Tool |
| SWIFT | True Customer Care - Interactive Sessions |
| Switchboard | LAMP-Based Web 2.0 Custom CRM Solution |
| SyFToR | Object-Oriented Human Resource Subsystems |
| Synchophe | Menuet/CX Animated Arcade Game |