Senior Project - Gene Pool

Methods for identifying chromosomal regions containing genes have been used to identify many quantitative trait loci (QTLs). The information available regarding this research is scattered among many facilities, and not all of the information is available to the public. A research group at the University of Colorado Health Sciences Center (UCHSC), Department of Pharmacology and Human Medical Genetics Program felt there was interest in the scientific research community involved in this research in creating a database that consolidates this existing research. UCHSC wanted to develop a genomics database and an accompanying website that will maintain information about the chromosomal regions that have been implicated as containing genes that influence addiction-related phenotypes.

This project provides an internet-based application containing a genomics database and an accompanying web site. The database holds a collection of data about chromosomal regions called quantitative trait loci (QTLs), and the web site provides the user with a graphical user interface (GUI) that is used to access the data in the database. It provides a means for scientists to view information about known QTLs and enables them to submit their own discoveries for inclusion into the database. The project was implemented in Perl using an Oracle database in a Solaris environment.