| CaeSaR | Image Cartoonization and Feature Recognition |
| cake | Color Graphics Printer Image Translator Generator |
| CAMPS | Standard Generalized Markup Language Viewer Toolkit |
| Canary | An Indoor Air Quality Monitoring System |
| capster | Interactive Set-Top Box Application Server |
| Card Shark | Electronic Flashcard Development System |
| Cardiac Arrest | Championship Hearts |
| ChaChing | Web Cache Appliance |
| chai | A Java-Based SNMP Command Layer |
| CHeShire | Championship for Palm: Hearts and Spades |
| Chocolate Rain | Google/YouTube Style Video Service |
| CLUMPRE | Text Analyzer to Support Natural Language Translation |
| codeHilt | 3D Visualization Tool for Parallel Physics Simulations |
| Comet | An Improved Software Configuration Management System |
| Communication Bytes | A Voice Capable Remote Information Presentation System |
| comrad | Web-Based Community Radio Administration |
| COMSAT | Ticketing and Alert System for MeetingOne |
| concord | Technical Conference Administration System |
| ConfesK | Web-based Conference Room Scheduling System |
| COWAbunga | Web-Based Support System for the Conference on World Affairs |
| cray watch | Machine Room Diagnostic Daemon |
| CraytoR | Simulation of the CRAY X/MP Process Scheduler |
| Cronos | A Prototype Software Model for the Board Game TITAN |
| Ctrans | C Version of the NCAR Computer Graphics Metafile Translator |
| Cyklops | Advanced Image Processing Utilities |
| Cyrano | Data Acquisition Tool for Hybrid Electric Vehicles |