Impact of Human Genome Research: Present and Future
Mervyn Young Memorial Lecture Series
on Computing Technology and Society
April 22, 2005
3:15pm - 4:50pm
RAMY C250
David H. Haussler
Howard Hughes Medical Institute
University of California, Santa Cruz
Eugene W. Myers
Howard Hughes Medical Institute
University of California, Berkeley
Janelia Farm
sponsored by
Department of Computer Science
Discovering the detailed structure of the human genome has enabled studies of
the relationship between genotypes and phenotypes, portending many exciting
scientific and social developments including personalized medicine and health
profiling. Complemented with advances in proteomics (the study of all the
proteins in a cell), micro-array expression analysis, and both light and
electron microscopy, we are beginning to understand how the program of the
genome is executed. Progress is accelerating, making this a very exciting
frontier of science.
In this talk for a general audience, prominent genome researchers
Eugene Myers and
David Haussler
will present personal perspectives on this area of research. They'll share
their ideas about the most important implications of the work, and what
developments we should expect over the next few decades.
. . .

David Haussler is an investigator for the
Howard Hughes Medical Institute,
he holds the UC Presidential Chair in
Computer Science
at the Santa Cruz campus, he is a consulting professor for the
Stanford Medical School and the
University of California San Francisco
Biopharmaceutical Sciences Department,
a fellow of the American Association for the Advancement of Science
(AAAS) and the
American Association for Artificial Intelligence
(AAAI),
member of the nominating committee for the
International Society for Computational Biology
and a member of the American Society of Human Genetics. He is a past chairman of the
Steering Committee for the Computational Learning Theory Conferences
(COLT),
an Associate Editor for the
Journal of Computational Biology,
and was an action editor for the journal Machine Learning.
He is currently Director of the
Center for Biomolecular Science & Engineering
at UCSC and scientific co-director of the multi-campus
Institute for Bioengineering, Biotechnology and Quantitative Biomedical Research
at USCF, UCB and UCSC.
Haussler holds a BA in Mathematics from
Connecticut College,
an MS in Applied Mathematics from
California Polytechnic State University, San Luis Obispo, and
a PhD in Computer Science from the
University of Colorado Boulder.
. . .

Eugene Myers joined the faculty of
Computer Science
at the University of California, Berkeley
at the start of 2003. He was formerly Vice President of Informatics Research at
Celera Genomics
for four years where he and his team determined the sequences of the
Drosophila, Human, and Mouse genomes using the whole genome shotgun technique
that he advocated in 1996. Prior to that Gene was on the faculty of the
University of Arizona for 18 years
and he received his PhD in Computer Science from the
University of Colorado in 1981.
His research interests include design of algorithms, pattern matching,
computer graphics, and computational molecular biology. His most recent academic
work has focused on algorithms for the central combinatorial problems involved
in DNA sequencing, and on a wide range of sequence and pattern comparison
problems. Among the tools he has developed are
BLAST --
a widely used tool for protein similarity searches,
FAKtory --
a system to support DNA sequencing projects,
Anrep -- a pattern matching language for applications in molecular biology,
and Mac- and PC-Molecule --
a molecular visualization tool for Apple and Wintel computers.
He was awarded the IEEE Third Millennium Achievement Award in 2000,
the Newcomb Cleveland Best Paper in Science award in 2001, and the ACM
Kanellakis Prize in 2002.
He was voted the most influential in bioinformatics in 2001 by
Genome Technology Magazine
and was elected to the
National Academy of Engineering in 2003.
. . .
The
Mervyn Young Memorial Lecture Series on Computing Technology and Society
addresses the relationship between innovation in computing technology
and changes in society.
Established by a 1952 alumnus of the College's Engineering Physics program,
the series is co-sponsored by the Department of Computer Science
and the College of Engineering and Applied Science.
The speakers are leaders from industry and distinguished academics.
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